Karoo Restaurant is located in Eastham, United States on 3 Main St #32B. Karoo Restaurant is rated 4.6 out of 5 in the category south african restaurant in United States. oo is a restaurant that celebrates the diversity of South African cuisine. Much like the United States, South Africa is a melting pot and the result is a culinary tradition that combines Dutch, British, Malaysian, Indian, Portuguese and native African flavors all together for something completely unique. Karoo is the brainchild of Chef Sanette Groenewald, who grew up in South Africa and fell in love with the food there. oo's menu is an interesting one. The recipes created in the kitchen can be traced back as far as eight generations. As noted before, the inspiration for these plates come from several different countries in the region so some dishes will be familiar while others will be interesting twists on existing classics. The specialty of the house is the national dish, bobotie. This is a curried yet mild meatloaf that has been baked and served with chutney and rice.